Biotinylated Human CLEC12A / MICL / CLL-1 Protein, Fc,Avitag? [CLA-H82F7]

Synonyms	-
Characteristics	This protein carries an Avi tag (Avitag?) at the N-terminus, followed by a human IgG1 Fc tag. The protein has a calculated MW of 51.9 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Reference	-
URL	https://www.acrobiosystems.com/P3414-Biotinylated-Human-CLEC12A--MICL--CLL-1-Protein-FcAvitag%E2%84%A2.html

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