Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag? (C-terminus) (MALS verified) [CLA-H82E9]

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サプライヤー: AcroBioSystems
カタログNo.: CLA-H82E9
製品名称: Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag? (C-terminus) (MALS verified)
タンパク質名: CLEC12A
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 27.3 kDa. The protein migrates as 35-53 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/clec12a-human-cla-h82e9

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