Biotinylated Human Claudin-9 Full Length Protein, His,Flag Tag&Avitag? (Detergent) [CL9-H85D3]

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サプライヤー: AcroBioSystems
カタログNo.: CL9-H85D3
製品名称: Biotinylated Human Claudin-9 Full Length Protein, His,Flag Tag&Avitag? (Detergent)
タンパク質名: Claudin-9
Species: Human
HOST: InsectCells

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the N-terminus and a Flag tag at the C-terminus followed by an Avi tag (Avitag?). The protein has a calculated MW of 28.2 kDa.
Endotoxin Level	N/A
Purity	90%
Description	Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus; it enables HCV entry into target cells just as efficiently as CLDN1.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/claudin-9-human-cl9-h85d3

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