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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
AcroBioSystems
カタログNo.
CL9-H5283
製品名称
Human Claudin-9 / CLDN9 Full Length Protein,?His,Twin-Strep?Tag (Nanodisc)
タンパク質名
Claudin-9
Species
Human
HOST
InsectCells
500ug: 3,462,600円
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100ug: 1,435,200円
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20ug: 386,000円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the N-terminus, and a twin-strep tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 22-25 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 90%
Description Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus; it enables HCV entry into target cells just as efficiently as CLDN1.
Reference -
URL https://www.acrobiosystems.com/products/protein/claudin-9-human-cl9-h5283

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