リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- CFD-R52H3
- 製品名称
- Rhesus macaque / Cynomolgus Complement Factor D / CFD Protein, His Tag (active enzyme)
- タンパク質名
- Complement Factor D
- Species
- Rhesus macaque / Cynomolgus
- HOST
- HEK293
Overview
Synonyms | - |
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Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 25-27 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 90% |
Description | Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease. |
Reference | - |
URL | https://www.acrobiosystems.com/P2780-Rhesus-macaque--Cynomolgus-Complement-Factor-D--CFD-Protein-His-Tag-%28active-enzyme%29.html |