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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- CDO-H52H3
- 製品名称
- Human CD45RO Protein, His Tag (MALS verified)
- タンパク質名
- CD45RO
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.4 kDa. The protein migrates as 70-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | CD45RO contains exon 3, 7 and 8 and lacks the RA, RB and RC exons of the CD45 gene. CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/cd45ro-human-cdo-h52h3 |
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