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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
AcroBioSystems
カタログNo.
CDL-M82Qb
製品名称
Biotinylated Mouse CD27 Ligand / CD70 Protein, His,Avitag?
タンパク質名
CD27 Ligand
Species
Mouse
HOST
HEK293
25ug: 96,500円
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200ug: 419,500円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 20.1 kDa. The protein migrates as 28-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level N/A
Purity 95%
Description Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.
Reference -
URL https://www.acrobiosystems.com/products/protein/cd27-ligand-mouse-cdl-m82qb

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