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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
CDH-H5251
製品名称
Human CD28H / IGPR-1 Protein, Fc Tag (MALS verified)
タンパク質名
CD28H
Species
Human
HOST
HEK293
1mg: 646800円
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100ug: 98000円
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Overview

Synonyms -
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.6 kDa. As a result of glycosylation, the protein migrates as 50-60 kDa under reducing (R) condition, and 90-116 kDa under non-reducing (NR) condition (SDS-PAGE).
Endotoxin Level 1.0 EU per μg
Purity 95%
Description CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Reference -
URL https://www.acrobiosystems.com/P2311-Human-CD28H--IGPR-1-Protein-Fc-Tag-%28MALS-verified%29.html

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