ACROBiosystems社 プロダクトリスト：Recombinant Protein
- Biotinylated Human LILRB5 / CD85c / LIR-8 Protein, Fc Tag, Avi Tag (Avitag)
|Characteristics||This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag). The protein has a calculated MW of 75.8 kDa. The protein migrates as 90-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Endotoxin Level||Less than 1.0 EU per μg by the LAL method.|
|Purity||>95% as determined by SDS-PAGE.|
|Description||Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation. Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.|
|Reference||(1)Liu T., et al., 2006, J. Proteome Res., 4 (6): 2070-2080.
(2)Thomas, R. et al., 2010, Clin. Rev. Allergy Immunol., 38: 159-162.
(3)Zheng, J. et al., 2012, Nature, 485: 656-660.