Alexa Fluor? 488 & Biotinylated-Labeled Mouse CD8 alpha Protein, His,Avitag? [CDA-MA2E3]

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サプライヤー: AcroBioSystems
カタログNo.: CDA-MA2E3
製品名称: Alexa Fluor? 488 & Biotinylated-Labeled Mouse CD8 alpha Protein, His,Avitag?
タンパク質名: CD8 alpha
Species: Mouse
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 22.5 kDa. The protein migrates as 33-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/cd8-alpha-mouse-cda-ma2e3

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