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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
CDA-H82W7
製品名称
Biotinylated Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His,Avitag?&Tag Free (MALS verified)
タンパク質名
CD8 alpha & beta
Species
Human
HOST
HEK293
200ug: 425600円
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25ug: 140000円
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Overview

Synonyms -
Characteristics Biotinylated Human CD8A&CD8B Heterodimer Protein, His,Avitag&Tag Free, produced by co-expression of CD8 alpha and CD8 beta, has a calculated MW of 26.0 kDa (CD8 alpha) and 22.1 kDa (CD8 beta). Subunit CD8 alpha is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and an Avi tag (Avitag?) and subunit CD8 beta contains no tag but a basic tail at the C-terminus. The protein migrates as 33 kDa and 35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 90%
Description Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
Reference -
URL https://www.acrobiosystems.com/P7106-Biotinylated-Human-CD8-alphabeta-%28CD8ACD8B%29-Heterodimer-Protein-HisAvitag%E2%84%A2Tag-Free-%28MALS-verified%29.html

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