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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
CDA-H5250
製品名称
Human LILRB3 / CD85a / ILT5 Protein, Fc Tag
タンパク質名
LILRB3
Species
Human
HOST
HEK293
100ug: 67,000円
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1mg: 437,000円
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Overview

Synonyms LILRB3,CD85a,ILT5
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.8 kDa. As a result of glycosylation, the protein migrates as 90-115 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >95% as determined by SDS-PAGE.
Description Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
Reference (1) Bashirova AA., et al., 2014, Immunogenetics.66(1):1-8.
(2) Huang J., et al., 2010, J Virol. 84(18):9463-9471.
(3) Pfistershammer K., et al., 2009, Blood. 114(11):2323-2332.
URL https://www.acrobiosystems.com/P2376-Human-LILRB3--CD85a--ILT5-Protein-Fc-Tag.html

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