検索リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト：Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- CD5-H5259
- 製品名称
- Human CD45 / PTPRC Protein, Llama IgG2b Fc Tag, low endotoxin
- タンパク質名
- CD45
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 88.6 kDa. The protein migrates as 200-250 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 0.05 EU per μg |
| Purity | 90% |
| Description | CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections. |
| Reference | - |
| URL | https://www.acrobiosystems.com/P5445-Human-CD45--PTPRC-Protein-Llama-IgG2b-Fc-Tag-low-endotoxin.html |
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