リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- CD4-C5256
- 製品名称
- Rhesus macaque CD4 Protein, Fc Tag (MALS verified)
- タンパク質名
- CD4
- Species
- Rhesus macaque
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 67.0 kDa. The protein migrates as 67-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients. |
Reference | - |
URL | https://www.acrobiosystems.com/P1599-Rhesus-macaque-CD4-Protein-Fc-Tag-%28MALS-verified%29.html |