リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- CD3-H52H1
- 製品名称
- Human CD133 Full Length Protein, His Tag (Nanodisc)
- タンパク質名
- CD133
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | The CD133 carries a polyhistidine tag at the C-terminus with calculated MW of 97.2 kDa and migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. The membrane scaffold protein (MSP1D1) has calculated MW of 24.7 kDa, and it migrates as 25 kDa under reducing (R) condition (SDS-PAGE). |
Endotoxin Level | 1.0 EU per μg |
Purity | 90% |
Description | Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. |
Reference | - |
URL | https://www.acrobiosystems.com/P3553-Human-CD133-Full-Length-Protein-His-Tag-%28Nanodisc%29.html |