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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
CD2-H82F8
製品名称
Biotinylated Human Nectin-2 / CD112 Protein, Fc,Avitag? (HPLC verified)
タンパク質名
Nectin-2
Species
Human
HOST
HEK293
200ug: 425600円
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25ug: 89320円
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Overview

Synonyms -
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 64.0 kDa. The protein migrates as 66 kDa under reducing (R) condition, and 130 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 95%
Description Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).
Reference -
URL https://www.acrobiosystems.com/P2360-Biotinylated-Human-Nectin-2--CD112-Protein-FcAvitag%E2%84%A2-%28HPLC-verified%29.html

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