ACROBiosystems社 プロダクトリスト：Recombinant Protein
- Biotinylated Human CD52, Fc Tag, Avi Tag (Avitag)
|Characteristics||This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag). The protein has a calculated MW of 29.7 kDa. As a result of glycosylation, the protein migrates as 38-45 kDa under reducing (R) condition, and 66-100 kDa under non-reducing (NR) condition (SDS-PAGE).|
|Endotoxin Level||Less than 1.0 EU per μg by the LAL method.|
|Purity||>95% as determined by SDS-PAGE.|
|Description||CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.|
|Reference||(1) Zhao Y., et al., 2017 ,Immunogenetics.
(2) Hersh C., et al., 2014, Immunotherapy. 6(3):249-59. (3) Zinzani PL., et al., 2012, Leuk Lymphoma. 53(5):789-9