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バイオ製品Bio Products

タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
AcroBioSystems
カタログNo.
CD2-H82A3
製品名称
Biotinylated Human Nectin-2 / CD112 Protein, Mouse IgG2a Fc,Avitag? (MALS verified)
タンパク質名
Nectin-2
Species
Human
HOST
HEK293
25ug: 96,500円
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200ug: 419,500円
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Overview

Synonyms -
Characteristics This protein carries a mouse IgG2a Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 64.1 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level N/A
Purity 95%
Description Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).
Reference -
URL https://www.acrobiosystems.com/products/protein/nectin-2-human-cd2-h82a3

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