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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- CC5-M52D9
- 製品名称
- Mouse CCR5 Protein, Flag,His Tag (Detergent)
- タンパク質名
- CCR5
- Species
- Mouse
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.1 kDa. The protein migrates as 40-43 kDa and 60-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | A chemokine receptor acting as the primary co-receptor for HIV-1 entry into host cells. Clinically validated by the FDA-approved inhibitor Maraviroc, CCR5 also regulates immune cell trafficking. Its blockade is being explored in oncology to reprogram the tumor microenvironment and enhance responses to checkpoint inhibitors. |
| Reference | 525 |
| URL | https://www.acrobiosystems.com/products/protein/ccr5-mouse-cc5-m52d9 |
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