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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- CA7-H5253
- 製品名称
- Human Cadherin-17 / CDH17 Protein, Fc Tag (Active, MALS verified)
- タンパク質名
- Cadherin-17
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.4 kDa. The protein migrates as 120-140 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/cadherin-17-human-ca7-h5253 |
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