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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
AcroBioSystems
カタログNo.
C5A-C5118
製品名称
Cynomolgus Complement C5a Protein, Tag Free
タンパク質名
Complement C5a
Species
Cynomolgus
HOST
E. coli
100ug: 104,600円
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1mg: 758,500円
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Overview

Synonyms -
Characteristics This protein carries no "tag". The protein has a calculated MW of 8.4 kDa. The protein migrates as 11 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level 1.0 EU per μg
Purity 95%
Description Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells; C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation; C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism; C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system; C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
Reference -
URL https://www.acrobiosystems.com/products/protein/complement-c5a-cynomolgus-c5a-c5118

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