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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
BCA-C5253
製品名称
Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc Tag
タンパク質名
BCMA
Species
Cynomolgus / Rhesus macaque
HOST
HEK293
100ug: 74,000円
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1mg: 483,000円
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Overview

Synonyms TNFRSF17,CD269,BCM,BCMA
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.1 kDa. As a result of glycosylation, the protein migrates as 37 kDa and 38-42 kDa under reducing (R) condition, and 60-66 kDa under non-reducing (NR) conditi
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >90% as determined by SDS-PAGE.
Description Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Reference (1) Hatzoglou A., et al., 2000, J. Immunol. 165:1322-1330.
(2) Gross J.A., et al., 2000, Nature 404:995-999.
(3) Yu G., et al., 2000, Nat. Immunol. 1:252-256.
URL https://www.acrobiosystems.com/P2367-Cynomolgus--Rhesus-macaque-BCMA--TNFRSF17--CD269-Protein-Fc-Tag.html

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