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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- BC1-H5120
- 製品名称
- Human Bcl-x / BCL2L1 Protein, His Tag
- タンパク質名
- Bcl-x
- Species
- Human
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.6 kDa. The protein migrates as 25-27 kDa under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | N/A |
| Purity | 95% |
| Description | Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/bcl-x-human-bc1-h5120 |
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