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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
BAR-M5259
製品名称
Mouse BAFFR / TNFRSF13C Protein, Fc Tag (HPLC verified)
タンパク質名
BAFFR
Species
Mouse
HOST
HEK293
1mg: 677600円
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20ug: 67200円
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Overview

Synonyms -
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 33.3 kDa. The protein migrates as 40-45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 95%
Description BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Reference -
URL https://www.acrobiosystems.com/P2321-Mouse-BAFFR--TNFRSF13C-Protein-Fc-Tag-%28HPLC-verified%29.html

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