リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- B77-H52H6
- 製品名称
- Human B7-H7 / HHLA2 Protein, His Tag (MALS verified)
- タンパク質名
- B7-H7
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
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Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.0 kDa. The protein migrates as 50-66 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members. |
Reference | - |
URL | https://www.acrobiosystems.com/P4539-Human-B7-H7--HHLA2-Protein-His-Tag-%28MALS-verified%29.html |