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タンパク質(癌免疫療法用)

ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
B75-M52H7
製品名称
Mouse B7-H5 / Gi24 / VISTA Protein
タンパク質名
B7-H5
Species
Mouse
HOST
HEK293
100ug: 74,000円
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1mg: 416,000円
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Overview

Synonyms B7-H5,SISP1,Gi24,VISTA
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.7kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >95% as determined by SDS-PAGE.
Description Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Reference (1) Sakr M.A., et al., 2010, Cancer Sci., 101: 2368-2374.
(2) Mayya V., et al ., 2009, Sci. Signal., 2: RA46-RA46.
URL https://www.acrobiosystems.com/P2330-Mouse-B7-H5-Protein-His-tag.html

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