ACROBiosystems社 プロダクトリスト：Recombinant Protein
- Mouse B7-H5 / Gi24 / VISTA Protein
|Characteristics||This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.7kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Endotoxin Level||Less than 1.0 EU per μg by the LAL method.|
|Purity||>95% as determined by SDS-PAGE.|
|Description||Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.|
|Reference||(1) Sakr M.A., et al., 2010, Cancer Sci., 101: 2368-2374.
(2) Mayya V., et al ., 2009, Sci. Signal., 2: RA46-RA46.