Biotinylated Human B7-H4 Protein, Avitag?,His Tag (recommended for biopanning) (MALS verified) [B74-H82E2]

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サプライヤー: AcroBioSystems
カタログNo.: B74-H82E2
製品名称: Biotinylated Human B7-H4 Protein, Avitag?,His Tag (recommended for biopanning) (MALS verified)
タンパク質名: B7-H4
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries an Avi tag (Avitag?) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 28 kDa. The protein migrates as 43-57 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/b7-h4-human-b74-h82e2

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