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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
APL-H52D1
製品名称
Human APRIL / TNFSF13 Protein, His,Flag Tag, active trimer (MALS verified)
タンパク質名
APRIL
Species
Human
HOST
HEK293
1mg: 711200円
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1mg: 776160円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag. The protein has a calculated MW of 50.2 kDa. The protein migrates as 50-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 95%
Description APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
Reference -
URL https://www.acrobiosystems.com/P3265-Human-APRIL--TNFSF13-Protein-HisFlag-Tag-active-trimer-%28MALS-verified%29.html

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