Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein, His Tag [AN4-H5243]

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 31-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
Reference	-
URL	https://www.acrobiosystems.com/P862-Human-Angiopoietin-like-4--ANGPTL4-%28166-406%29-Protein-His-Tag.html

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