Description |
ALPPL2 is specifically highly expressed in na?ve pluripotent stem cells. Moreover, in na?ve state somatic cell reprogramming, na?ve-primed transformation and other systems, the use of the ALPPL2 promoter-driven fluorescent reporter system can specifically indicate the establishment or withdrawal of na?ve state pluripotency, thereby identifying ALPPL2 as na?ve state pluripotent. specific cell surface markers. Some studies have found that knockout of ALPPL2 can specifically affect the establishment, stability and maintenance of na?ve state pluripotency, proving that ALPPL2 protein is a functional na?ve state surface molecular marker. |