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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
AcroBioSystems
カタログNo.
ACA-M52H3
製品名称
Mouse Activin RIIA / ACVR2A Protein, His Tag, low endotoxin (SPR?& HPLC verified)
タンパク質名
Activin RIIA
Species
Mouse
HOST
HEK293
200ug: 80,400 円
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1mg: 297,500 円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.3 kDa. The protein migrates as 25-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 0.01 EU per μg
Purity 90%
Description Activin receptor type-2A (ACVR2A) is also known as activin receptor type IIA, ACTR-IIA, ACTRIIA, and ACVR2, and is a single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily, the TKL Ser/Thr protein kinase family, and the TGFB receptor subfamily. Upon ligand binding, ACVR2A forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors,?which then phosphorylate and activate SMAD transcriptional regulators. ACVR2A also serves as a receptor for activin A, activin B, and inhibin A?(the latter in complex with betaglycan).?Two?type II activin receptors?(ACVR2A and ACVR2B)?have been identified, which bind different activins with distinct affinities.
Reference 72
URL https://www.acrobiosystems.com/products/protein/activin-riia-mouse-aca-m52h3

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