Biotinylated Human / Cynomolgus Activin RIIA Protein, Avitag?,Fc Tag (MALS verified) [ACA-H82F4]

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サプライヤー: AcroBioSystems
カタログNo.: ACA-H82F4
製品名称: Biotinylated Human / Cynomolgus Activin RIIA Protein, Avitag?,Fc Tag (MALS verified)
タンパク質名: Activin RIIA
Species: Human / Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	This protein carries an Avi tag (Avitag?) at the N-terminus, followed by a human IgG1 Fc tag. The protein has a calculated MW of 41.5 kDa. The protein migrates as 53-63 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	Activin receptor type-2A (ACVR2A) is also known as activin receptor type IIA, ACTR-IIA, ACTRIIA, and ACVR2, and is a single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily, the TKL Ser/Thr protein kinase family, and the TGFB receptor subfamily. Upon ligand binding, ACVR2A forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors,?which then phosphorylate and activate SMAD transcriptional regulators. ACVR2A also serves as a receptor for activin A, activin B, and inhibin A?(the latter in complex with betaglycan).?Two?type II activin receptors?(ACVR2A and ACVR2B)?have been identified, which bind different activins with distinct affinities.
Reference	70
URL	https://www.acrobiosystems.com/products/protein/activin-riia-human-cynomolgus-aca-h82f4

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