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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- ACA-H5243
- 製品名称
- Human / Cynomolgus Activin RIIA / ACVR2A Protein, His Tag (MALS & SPR verified)
- タンパク質名
- Activin RIIA
- Species
- Human / Cynomolgus
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 15.4 kDa. The protein migrates as 29-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Activin receptor type-2A (ACVR2A) is also known as Activin receptor type IIA, ACTR-IIA, ACTRIIA and ACVR2,which is single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/activin-riia-human-cynomolgus-aca-h5243 |
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