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バイオ製品Bio Products

タンパク質、抗体、アッセイキット

タンパク質カタログ

サプライヤー
AcroBioSystems
カタログNo.
ACA-H424x
製品名称
Human Latent Activin A / INHBA Protein, His Tag
タンパク質名
Activin A
Species
Human
HOST
HEK293
100ug: 114800円
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1mg: 862400円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 13.0 kDa (mature) and 32.0 kDa (pro). As a result of glycosylation and Interchain disulfide bond, the protein migrates as 15 kDa (mature) and 43-48 kDa (pro) under reducing (R) condition, and 27 kDa (mature), 43-48 kDa (pro) and 60 kDa (pro & mature) under non-reducing (NR) condition (SDS-PAGE).
Endotoxin Level 1.0 EU per μg
Purity 95%
Description Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various β subunits (βA, βB, βC, and βE in mammals), while Inhibins are heterodimers of a unique α subunit and one of the β subunits. Activin A is a widely expressed homodimer of two βA chains. The βA subunit can also heterodimerize with a βB or βC subunit to form Activin AB and Activin AC, respectively. The 14 kDa mature human βA chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat βA.
Reference -
URL https://www.acrobiosystems.com/P2190-Human-Latent-Activin-A--INHBA-Protein-His-Tag.html

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