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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
CC6-M5222
製品名称
Mouse CCL6 / C10 Protein
タンパク質名
CCL6
Species
Mouse
HOST
HEK293
20ug: 47,000円
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50ug: 89,000円
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Overview

Synonyms CCL6,SCYA6,C10,MRP-1
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.4 kDa. The protein migrates as 14 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >95% as determined by SDS-PAGE.
Description Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM?CSF. CCL6 has only been identified in rodents, A?human?homologue?for?mouse?CCL6?has?not?been?identified.??The?mCCL6?cDNA?encodes?a?116?amino?acid?residue?precursor?protein?with?a?hydrophobic?signal?peptide?that?is?cleaved?to?yield?a?95?amino?acid?residue?mature?protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where?it?is?strongly?induced?upon?GM?CSF?(Cat. # GMF-H4214) stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 (Cat. # IL4-H4218) in mouse macrophages and by cytokine IL?13 (Cat. # IL3-H4210) in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
Reference (1) Orlofsky, et al., 1991, Cell Regul. 2 (5), 403-412.
(2) Ma., et al., 2004, J Immunol.172(3):1872-81.
(3) Berger., et al., 1993, DNA Cell Biol. 12 (9), 839-847.
(4) Kanno M, et al., 2005, J Neuroimmunol. 167(1-2): 72-80.
URL http://www.acrobiosystems.com/P360-Mouse-CCL6-ProteinHEK293-expressed.html

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