ACROBiosystems社 プロダクトリスト：Recombinant Protein
- Human ANGPTL7 / CDT6 Protein
- 100ug: 87,000円
|Characteristics||This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39 kDa. The protein migrates as 38-40 kDa and 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Endotoxin Level||Less than 1.0 EU per μg by the LAL method.|
|Purity||>85% as determined by SDS-PAGE.|
|Description||Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.|
|Reference||(1) Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788.
(2) Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693.
(3) Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.