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| MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. |
| • Over 100,000 bioactive molecules in stock |
| • Target 1,000+ key proteins in 20+ signaling pathways |
| • Quality reports (LC/MS, NMR and HPLC) for each product |
| • Release more than 1,000 latest biochemicals per month |
| • Data sheet with detailed biological information |
| • High purity & competitive prices |
| • Delivery within 24 hours |
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CAS No.: 2832887-40-6
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Research Area: Phosphatase/Cdc25C/Cancer
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A potent Cdc25 phosphatase inhibitor with IC50 values of 150 nM, 190 nM, and 60 nM for Cdc25A, and Cdc25B, and Cdc25C, respectively. |
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As a relatively selective Cdc25C inhibitor with a broad-spectrum anti-cancer activity. |
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Solubility: DMSO: 25 mg/mL (61.00 mM; Need ultrasonic)
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CAS No.: 1381769-23-8
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Research Area: Phosphatase/STEP/Neurological Disease
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A selective striatal-enriched protein tyrosine phosphatase (STEP) inhibitor with an IC50 of 24.6 nM. |
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Forms a reversible covalent bond with the catalytic cysteine in STEP, and increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B. |
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Possesses anxiolytic, anticataleptic and antidepressant properties. |
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Solubility: DMSO: 100 mg/mL (280.99 mM; Need ultrasonic)
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CAS No.: 36505-84-7
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Research Area: 5-HT Receptor/Anxiety Disorders
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An orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. |
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An anxiolytic agent, and has the potential for the generalized anxiety disorder research. |
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The anxiolytic and anti-depressant effects are produced by activating 5-HT1A autoreceptors and 5-HT1A heteroreceptors, respectively. |
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Solubility: DMSO: 100 mg/mL (259.40 mM; Need ultrasonic)
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CAS No.: 257277-05-7
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Research Area: Bacterial/Fungal/Oral Mucositis
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An anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. |
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Kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. |
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Has the potential for preventing oral mucositis caused by chemotherapy and radiation therapy. |
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Solubility: H2O: 100 mg/mL (52.62 mM; Need ultrasonic)
DMSO: 25 mg/mL (13.16 mM; Need ultrasonic)
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CAS No.: 792898-18-1
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Research Area: Spermine Oxidase/Polyamine Catabolism
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A selective, competitive allosteric human spermine oxidase (hSMOX) inhibitor with an IC50 of 50 nM. |
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Has potential anticancer and anti-inflammatory activities for the study of polyamine catabolic disorders. |
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Solubility: DMSO: 100 mg/mL (324.30 mM; Need ultrasonic)
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| Transfection Reagents |
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| Transfection refers to the introduction of exogenous molecules such as DNA, RNA or proteins into eukaryotic cells using various methods. Transfection techniques are useful as an analytical tool to characterize gene function, protein synthesis, cell growth and development. MCE offers a wide variety of cell transfection reagents. Click here for an up-to-date list of MCE Kits! |
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| Restriction Endonucleases |
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| MCE Fast Restriction Endonucleases are coming. Universal buffer, fast digestion, extremely low asterisk activity all make your digestion reactions simple and efficient! Click here for an up-to-date list of MCE Restriction Endonuclease! |
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| MCE Isotope-labeled Compounds |
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Latest Publications Citing Use of MCE Products |
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Nature.
2024 Feb;626(7998):411-418. |
Cell.
2024 Feb 1;187(3):609-623.e21. |
Cell.
2024 Feb 1;187(3):624-641.e23. |
Cell.
2024 Feb 15;187(4):882-896.e17. |
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Products are for research use only and are not intended for human use. We do not sell to patients.
We respect your privacy and do not share or sell your information to third parties. |
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